In the largest study conducted on the neurogenetics of oligodendrogliomas, scientists have discovered that a mutation in the gene TCF12 may very well lead to the development of this cancer. Professor Richard Houlston, Professor of Molecular and Population Genetics at The Institute of Cancer Research, London, said:"Our in-depth study has set out many of the genetic defects that cause this rare but highly aggressive form of brain cancer -- including identifying a gene mutation that appears in particularly fast-growing forms.
"Anaplastic oligodendrogliomas are difficult to remove by surgery and don't respond well to other forms of treatment. We hope this new information might be used to discover new targeted therapies, offering patients a better chance at survival from this aggressive cancer."
"Anaplastic oligodendrogliomas are difficult to remove by surgery and don't respond well to other forms of treatment. We hope this new information might be used to discover new targeted therapies, offering patients a better chance at survival from this aggressive cancer."