Cancer stem cells are thought to be the main drivers of tumor growth. Aside from being resistant to conventional interventions, cancer stem cells are believed to contain the capability of self-regeneration and repopulation of tumor cells, results in cancer recurrence. UCLA researchers have received awards from the California Institute of Regenerative Medicine to run two clinical trials in 2014 aimed at stem cell targeted therapy for cancer and the first in-human testing of stem cell gene therapy for sickle cell disease.
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